{
  "schemaVersion": "2.0.0",
  "dataVersion": "2026-08-11.3",
  "generatedAt": "2026-08-11T00:00:00Z",
  "title": {
    "ko": "질병별 MPA·VPA 시간–HR 자료",
    "en": "Disease-specific MPA/VPA time–HR data"
  },
  "calculation": {
    "timeMeaning": {
      "ko": "웨어러블에서 산출된 평소 일평균 활동량이 m분/일인 집단과 m+1분/일인 집단의 관찰 모형 HR 차이",
      "en": "Observational model HR contrast between groups whose wearable-derived habitual mean activity is m versus m+1 minutes/day"
    },
    "relativeHazardDifferenceFromReferencePercent": "100 * (1 - HR[m])",
    "nextMinuteHazardRatioChange": "HR[m+1] - HR[m]",
    "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": "100 * (HR[m] - HR[m+1])",
    "acuteOneMinuteExerciseEffectAvailable": false,
    "absoluteRiskCalculationAvailable": false,
    "causalEffectClaimed": false
  },
  "rendering": {
    "authorPublishedSourceCurve": {
      "xField": "points[].minutePerDay",
      "primaryYField": "points[].hazardRatio",
      "confidenceIntervalFields": [
        "points[].lowerConfidenceBound",
        "points[].upperConfidenceBound"
      ],
      "localChangeField": "points[].nextMinuteRelativeHazardDifferenceIncreasePercentagePoints"
    },
    "reportedCategories": {
      "xField": "reportedCategories[].reportedRangeLabel",
      "primaryYField": "reportedCategories[].hazardRatio",
      "confidenceIntervalFields": [
        "reportedCategories[].lowerConfidenceBound",
        "reportedCategories[].upperConfidenceBound"
      ],
      "minuteCurveAvailable": false
    }
  },
  "globalLimitations": [
    {
      "ko": "1분 간격 값은 오늘 운동을 1분 더 한 효과가 아니라, 웨어러블에서 산출된 평소 일평균 활동량이 1분/일 다른 집단 간 관찰 모형 비교입니다.",
      "en": "One-minute-step values are observational model contrasts between groups whose wearable-derived habitual mean activity differs by one minute/day; they are not the effect of exercising one extra minute today."
    },
    {
      "ko": "HR 기반 상대차이로서 절대 발병확률 감소가 아닙니다.",
      "en": "These are HR-based relative contrasts, not absolute event-probability reductions."
    },
    {
      "ko": "범주형 연구에는 임의 평균·일평균 환산·분별 보간을 적용하지 않았습니다.",
      "en": "No invented averages, daily conversions, or minute interpolation are applied to categorical studies."
    },
    {
      "ko": "자료 대부분이 UK Biobank에서 나와 연구들을 독립 재현으로 합산할 수 없습니다.",
      "en": "Most data come from UK Biobank and cannot be counted as independent replications."
    }
  ],
  "series": [
    {
      "id": "mace.moderate.biswas-2025",
      "renderingGroup": "mace.biswas-2025",
      "evidenceForm": "authorPublishedSourceCurve",
      "minuteSeriesStatus": "availableFromAuthorPublishedSourceCurve",
      "recommendedForRendering": true,
      "outcome": {
        "id": "mace",
        "domain": "cardiovascular",
        "label": {
          "ko": "주요 심혈관 사건(MACE)",
          "en": "Major adverse cardiovascular events (MACE)"
        },
        "endpoint": {
          "ko": "심혈관 사망 또는 심근경색·뇌졸중·심부전 발생의 복합결과",
          "en": "Composite of cardiovascular death or incident myocardial infarction, stroke, or heart failure"
        }
      },
      "intensity": {
        "id": "moderate",
        "abbreviation": "MPA",
        "label": {
          "ko": "중강도 신체활동(MPA)",
          "en": "Moderate-intensity physical activity (MPA)"
        }
      },
      "source": {
        "id": "biswas.nature-communications.2025.corrected",
        "citation": "Biswas RK, et al. Wearable device-based health equivalence of different physical activity intensities against mortality, cardiometabolic disease, and cancer. Nature Communications. 2025;16:8315.",
        "journal": "Nature Communications",
        "publicationYear": 2025,
        "doi": "10.1038/s41467-025-63475-2",
        "url": "https://www.nature.com/articles/s41467-025-63475-2",
        "sourceDataUrl": "https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41467-025-63475-2/MediaObjects/41467_2025_63475_MOESM10_ESM.xlsx",
        "journalQuartile": "Q1",
        "quartileReviewedAt": "2026-08-11T00:00:00Z",
        "overlapGroup": "uk-biobank-accelerometry"
      },
      "population": {
        "participantCount": 67314,
        "eventCount": 2359,
        "meanAgeYears": 61.6,
        "ageSDYears": 7.9,
        "femalePercent": 56.4,
        "whitePercent": 96.2
      },
      "exposure": {
        "reportedUnit": "minutePerDay",
        "timeBasis": "habitualMeanMinutePerDayFromWearableAssessment",
        "referenceMinutePerDay": 0,
        "authorSourceCurveGridStepMinute": 0.01,
        "sourceCurveMaximumMinutePerDay": 90.78,
        "includedIntegerMinuteMaximum": 90,
        "sourceSampling": "Exact author-published source-curve rows where Primary_exposure is an integer; no averaging and no interpolation"
      },
      "model": {
        "type": "FineGraySubdistributionHazardSpline",
        "mutuallyAdjustedForOtherIntensityEnergyExpenditure": true,
        "referentMinutePerDay": 0,
        "sourceDataUrl": "https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41467-025-63475-2/MediaObjects/41467_2025_63475_MOESM10_ESM.xlsx"
      },
      "points": [
        {
          "minutePerDay": 0,
          "hazardRatio": 1,
          "lowerConfidenceBound": 1,
          "upperConfidenceBound": 1,
          "relativeHazardDifferenceFromReferencePercent": 0,
          "nextMinuteHazardRatio": 0.984613,
          "nextMinuteHazardRatioChange": -0.015387,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 1.539
        },
        {
          "minutePerDay": 1,
          "hazardRatio": 0.984613,
          "lowerConfidenceBound": 0.978942,
          "upperConfidenceBound": 0.990317,
          "relativeHazardDifferenceFromReferencePercent": 1.539,
          "nextMinuteHazardRatio": 0.969464,
          "nextMinuteHazardRatioChange": -0.01515,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 1.515
        },
        {
          "minutePerDay": 2,
          "hazardRatio": 0.969464,
          "lowerConfidenceBound": 0.958328,
          "upperConfidenceBound": 0.980729,
          "relativeHazardDifferenceFromReferencePercent": 3.054,
          "nextMinuteHazardRatio": 0.954547,
          "nextMinuteHazardRatioChange": -0.014917,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 1.492
        },
        {
          "minutePerDay": 3,
          "hazardRatio": 0.954547,
          "lowerConfidenceBound": 0.938148,
          "upperConfidenceBound": 0.971233,
          "relativeHazardDifferenceFromReferencePercent": 4.545,
          "nextMinuteHazardRatio": 0.93986,
          "nextMinuteHazardRatioChange": -0.014687,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 1.469
        },
        {
          "minutePerDay": 4,
          "hazardRatio": 0.93986,
          "lowerConfidenceBound": 0.918393,
          "upperConfidenceBound": 0.961829,
          "relativeHazardDifferenceFromReferencePercent": 6.014,
          "nextMinuteHazardRatio": 0.925399,
          "nextMinuteHazardRatioChange": -0.014461,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 1.446
        },
        {
          "minutePerDay": 5,
          "hazardRatio": 0.925399,
          "lowerConfidenceBound": 0.899053,
          "upperConfidenceBound": 0.952516,
          "relativeHazardDifferenceFromReferencePercent": 7.46,
          "nextMinuteHazardRatio": 0.91116,
          "nextMinuteHazardRatioChange": -0.014239,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 1.424
        },
        {
          "minutePerDay": 6,
          "hazardRatio": 0.91116,
          "lowerConfidenceBound": 0.880121,
          "upperConfidenceBound": 0.943293,
          "relativeHazardDifferenceFromReferencePercent": 8.884,
          "nextMinuteHazardRatio": 0.89714,
          "nextMinuteHazardRatioChange": -0.01402,
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        },
        {
          "minutePerDay": 7,
          "hazardRatio": 0.89714,
          "lowerConfidenceBound": 0.861588,
          "upperConfidenceBound": 0.934159,
          "relativeHazardDifferenceFromReferencePercent": 10.286,
          "nextMinuteHazardRatio": 0.883336,
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          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 1.38
        },
        {
          "minutePerDay": 8,
          "hazardRatio": 0.883336,
          "lowerConfidenceBound": 0.843445,
          "upperConfidenceBound": 0.925114,
          "relativeHazardDifferenceFromReferencePercent": 11.666,
          "nextMinuteHazardRatio": 0.869745,
          "nextMinuteHazardRatioChange": -0.013592,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 1.359
        },
        {
          "minutePerDay": 9,
          "hazardRatio": 0.869745,
          "lowerConfidenceBound": 0.825684,
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          "nextMinuteHazardRatio": 0.856362,
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        },
        {
          "minutePerDay": 10,
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          "lowerConfidenceBound": 0.808297,
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          "minutePerDay": 11,
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          "minutePerDay": 12,
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          "upperConfidenceBound": 0.889821,
          "relativeHazardDifferenceFromReferencePercent": 16.975,
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          "nextMinuteHazardRatioChange": -0.012685,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 1.268
        },
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          "minutePerDay": 13,
          "hazardRatio": 0.817564,
          "lowerConfidenceBound": 0.758477,
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          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 1.24
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          "lowerConfidenceBound": 0.71276,
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        },
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          "minutePerDay": 17,
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          "minutePerDay": 18,
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          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.904
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        {
          "minutePerDay": 34,
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        {
          "minutePerDay": 35,
          "hazardRatio": 0.636456,
          "lowerConfidenceBound": 0.543185,
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          "minutePerDay": 36,
          "hazardRatio": 0.632974,
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        {
          "minutePerDay": 37,
          "hazardRatio": 0.629806,
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        {
          "minutePerDay": 38,
          "hazardRatio": 0.626935,
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          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.259
        },
        {
          "minutePerDay": 39,
          "hazardRatio": 0.624345,
          "lowerConfidenceBound": 0.531142,
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        {
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        {
          "minutePerDay": 41,
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        {
          "minutePerDay": 42,
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          "lowerConfidenceBound": 0.52545,
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          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.161
        },
        {
          "minutePerDay": 43,
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          "lowerConfidenceBound": 0.52408,
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          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.14
        },
        {
          "minutePerDay": 44,
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        {
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        {
          "minutePerDay": 88,
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          "nextMinuteHazardRatioChange": 0.000339,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": -0.034
        },
        {
          "minutePerDay": 89,
          "hazardRatio": 0.621125,
          "lowerConfidenceBound": 0.511454,
          "upperConfidenceBound": 0.754313,
          "relativeHazardDifferenceFromReferencePercent": 37.887,
          "nextMinuteHazardRatio": 0.621465,
          "nextMinuteHazardRatioChange": 0.00034,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": -0.034
        },
        {
          "minutePerDay": 90,
          "hazardRatio": 0.621465,
          "lowerConfidenceBound": 0.510565,
          "upperConfidenceBound": 0.756453,
          "relativeHazardDifferenceFromReferencePercent": 37.853,
          "nextMinuteHazardRatio": null,
          "nextMinuteHazardRatioChange": null,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": null
        }
      ],
      "limitations": [
        {
          "ko": "각 행은 하루 한 번의 운동 효과가 아니라, 평소 일평균 활동시간이 다른 집단을 비교한 관찰 모형값입니다.",
          "en": "Each row is an observational model contrast between habitual mean daily activity doses, not the effect of one exercise minute performed today."
        },
        {
          "ko": "상대 HR 차이이며 개인의 절대위험 변화나 인과효과가 아닙니다.",
          "en": "This is a relative hazard contrast, not an individual absolute-risk change or causal effect."
        },
        {
          "ko": "연령·성별·인종은 보정변수이며, 이 곡선은 해당 집단별 효과곡선이 아닙니다.",
          "en": "Age, sex, and ethnicity were adjustment variables; these are not subgroup-specific curves."
        }
      ]
    },
    {
      "id": "mace.vigorous.biswas-2025",
      "renderingGroup": "mace.biswas-2025",
      "evidenceForm": "authorPublishedSourceCurve",
      "minuteSeriesStatus": "availableFromAuthorPublishedSourceCurve",
      "recommendedForRendering": true,
      "outcome": {
        "id": "mace",
        "domain": "cardiovascular",
        "label": {
          "ko": "주요 심혈관 사건(MACE)",
          "en": "Major adverse cardiovascular events (MACE)"
        },
        "endpoint": {
          "ko": "심혈관 사망 또는 심근경색·뇌졸중·심부전 발생의 복합결과",
          "en": "Composite of cardiovascular death or incident myocardial infarction, stroke, or heart failure"
        }
      },
      "intensity": {
        "id": "vigorous",
        "abbreviation": "VPA",
        "label": {
          "ko": "고강도 신체활동(VPA)",
          "en": "Vigorous-intensity physical activity (VPA)"
        }
      },
      "source": {
        "id": "biswas.nature-communications.2025.corrected",
        "citation": "Biswas RK, et al. Wearable device-based health equivalence of different physical activity intensities against mortality, cardiometabolic disease, and cancer. Nature Communications. 2025;16:8315.",
        "journal": "Nature Communications",
        "publicationYear": 2025,
        "doi": "10.1038/s41467-025-63475-2",
        "url": "https://www.nature.com/articles/s41467-025-63475-2",
        "sourceDataUrl": "https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41467-025-63475-2/MediaObjects/41467_2025_63475_MOESM10_ESM.xlsx",
        "journalQuartile": "Q1",
        "quartileReviewedAt": "2026-08-11T00:00:00Z",
        "overlapGroup": "uk-biobank-accelerometry"
      },
      "population": {
        "participantCount": 67314,
        "eventCount": 2359,
        "meanAgeYears": 61.6,
        "ageSDYears": 7.9,
        "femalePercent": 56.4,
        "whitePercent": 96.2
      },
      "exposure": {
        "reportedUnit": "minutePerDay",
        "timeBasis": "habitualMeanMinutePerDayFromWearableAssessment",
        "referenceMinutePerDay": 0,
        "authorSourceCurveGridStepMinute": 0.01,
        "sourceCurveMaximumMinutePerDay": 27.28,
        "includedIntegerMinuteMaximum": 27,
        "sourceSampling": "Exact author-published source-curve rows where Primary_exposure is an integer; no averaging and no interpolation"
      },
      "model": {
        "type": "FineGraySubdistributionHazardSpline",
        "mutuallyAdjustedForOtherIntensityEnergyExpenditure": true,
        "referentMinutePerDay": 0,
        "sourceDataUrl": "https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41467-025-63475-2/MediaObjects/41467_2025_63475_MOESM10_ESM.xlsx"
      },
      "points": [
        {
          "minutePerDay": 0,
          "hazardRatio": 1,
          "lowerConfidenceBound": 1,
          "upperConfidenceBound": 1,
          "relativeHazardDifferenceFromReferencePercent": 0,
          "nextMinuteHazardRatio": 0.918065,
          "nextMinuteHazardRatioChange": -0.081935,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 8.194
        },
        {
          "minutePerDay": 1,
          "hazardRatio": 0.918065,
          "lowerConfidenceBound": 0.895419,
          "upperConfidenceBound": 0.941283,
          "relativeHazardDifferenceFromReferencePercent": 8.194,
          "nextMinuteHazardRatio": 0.843826,
          "nextMinuteHazardRatioChange": -0.074239,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 7.424
        },
        {
          "minutePerDay": 2,
          "hazardRatio": 0.843826,
          "lowerConfidenceBound": 0.803069,
          "upperConfidenceBound": 0.886652,
          "relativeHazardDifferenceFromReferencePercent": 15.617,
          "nextMinuteHazardRatio": 0.779195,
          "nextMinuteHazardRatioChange": -0.064631,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 6.463
        },
        {
          "minutePerDay": 3,
          "hazardRatio": 0.779195,
          "lowerConfidenceBound": 0.724875,
          "upperConfidenceBound": 0.837586,
          "relativeHazardDifferenceFromReferencePercent": 22.08,
          "nextMinuteHazardRatio": 0.725574,
          "nextMinuteHazardRatioChange": -0.053622,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 5.362
        },
        {
          "minutePerDay": 4,
          "hazardRatio": 0.725574,
          "lowerConfidenceBound": 0.661913,
          "upperConfidenceBound": 0.795356,
          "relativeHazardDifferenceFromReferencePercent": 27.443,
          "nextMinuteHazardRatio": 0.683333,
          "nextMinuteHazardRatioChange": -0.04224,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 4.224
        },
        {
          "minutePerDay": 5,
          "hazardRatio": 0.683333,
          "lowerConfidenceBound": 0.613915,
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          "minutePerDay": 20,
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        {
          "minutePerDay": 22,
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          "nextMinuteHazardRatioChange": -0.000643,
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        {
          "minutePerDay": 23,
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          "nextMinuteHazardRatioChange": -0.000642,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.064
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        {
          "minutePerDay": 24,
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          "lowerConfidenceBound": 0.475216,
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          "nextMinuteHazardRatioChange": -0.000642,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.064
        },
        {
          "minutePerDay": 25,
          "hazardRatio": 0.562791,
          "lowerConfidenceBound": 0.470817,
          "upperConfidenceBound": 0.672731,
          "relativeHazardDifferenceFromReferencePercent": 43.721,
          "nextMinuteHazardRatio": 0.56215,
          "nextMinuteHazardRatioChange": -0.000641,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.064
        },
        {
          "minutePerDay": 26,
          "hazardRatio": 0.56215,
          "lowerConfidenceBound": 0.466263,
          "upperConfidenceBound": 0.677755,
          "relativeHazardDifferenceFromReferencePercent": 43.785,
          "nextMinuteHazardRatio": 0.56151,
          "nextMinuteHazardRatioChange": -0.00064,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.064
        },
        {
          "minutePerDay": 27,
          "hazardRatio": 0.56151,
          "lowerConfidenceBound": 0.461585,
          "upperConfidenceBound": 0.683066,
          "relativeHazardDifferenceFromReferencePercent": 43.849,
          "nextMinuteHazardRatio": null,
          "nextMinuteHazardRatioChange": null,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": null
        }
      ],
      "limitations": [
        {
          "ko": "각 행은 하루 한 번의 운동 효과가 아니라, 평소 일평균 활동시간이 다른 집단을 비교한 관찰 모형값입니다.",
          "en": "Each row is an observational model contrast between habitual mean daily activity doses, not the effect of one exercise minute performed today."
        },
        {
          "ko": "상대 HR 차이이며 개인의 절대위험 변화나 인과효과가 아닙니다.",
          "en": "This is a relative hazard contrast, not an individual absolute-risk change or causal effect."
        },
        {
          "ko": "연령·성별·인종은 보정변수이며, 이 곡선은 해당 집단별 효과곡선이 아닙니다.",
          "en": "Age, sex, and ethnicity were adjustment variables; these are not subgroup-specific curves."
        }
      ]
    },
    {
      "id": "cardiovascularMortality.moderate.biswas-2025",
      "renderingGroup": "cardiovascularMortality.biswas-2025",
      "evidenceForm": "authorPublishedSourceCurve",
      "minuteSeriesStatus": "availableFromAuthorPublishedSourceCurve",
      "recommendedForRendering": true,
      "outcome": {
        "id": "cardiovascularMortality",
        "domain": "cardiovascular",
        "label": {
          "ko": "심혈관 사망",
          "en": "Cardiovascular mortality"
        },
        "endpoint": {
          "ko": "심혈관질환에 의한 사망",
          "en": "Death attributed to cardiovascular disease"
        }
      },
      "intensity": {
        "id": "moderate",
        "abbreviation": "MPA",
        "label": {
          "ko": "중강도 신체활동(MPA)",
          "en": "Moderate-intensity physical activity (MPA)"
        }
      },
      "source": {
        "id": "biswas.nature-communications.2025.corrected",
        "citation": "Biswas RK, et al. Wearable device-based health equivalence of different physical activity intensities against mortality, cardiometabolic disease, and cancer. Nature Communications. 2025;16:8315.",
        "journal": "Nature Communications",
        "publicationYear": 2025,
        "doi": "10.1038/s41467-025-63475-2",
        "url": "https://www.nature.com/articles/s41467-025-63475-2",
        "sourceDataUrl": "https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41467-025-63475-2/MediaObjects/41467_2025_63475_MOESM10_ESM.xlsx",
        "journalQuartile": "Q1",
        "quartileReviewedAt": "2026-08-11T00:00:00Z",
        "overlapGroup": "uk-biobank-accelerometry"
      },
      "population": {
        "participantCount": 67499,
        "eventCount": 545,
        "meanAgeYears": 61.6,
        "ageSDYears": 7.9,
        "femalePercent": 56.4,
        "whitePercent": 96.2
      },
      "exposure": {
        "reportedUnit": "minutePerDay",
        "timeBasis": "habitualMeanMinutePerDayFromWearableAssessment",
        "referenceMinutePerDay": 0,
        "authorSourceCurveGridStepMinute": 0.01,
        "sourceCurveMaximumMinutePerDay": 90.78,
        "includedIntegerMinuteMaximum": 90,
        "sourceSampling": "Exact author-published source-curve rows where Primary_exposure is an integer; no averaging and no interpolation"
      },
      "model": {
        "type": "FineGraySubdistributionHazardSpline",
        "mutuallyAdjustedForOtherIntensityEnergyExpenditure": true,
        "referentMinutePerDay": 0,
        "sourceDataUrl": "https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41467-025-63475-2/MediaObjects/41467_2025_63475_MOESM10_ESM.xlsx"
      },
      "points": [
        {
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          "hazardRatio": 1,
          "lowerConfidenceBound": 1,
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        },
        {
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        },
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          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": -0.32
        },
        {
          "minutePerDay": 90,
          "hazardRatio": 0.688259,
          "lowerConfidenceBound": 0.458826,
          "upperConfidenceBound": 1.032417,
          "relativeHazardDifferenceFromReferencePercent": 31.174,
          "nextMinuteHazardRatio": null,
          "nextMinuteHazardRatioChange": null,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": null
        }
      ],
      "limitations": [
        {
          "ko": "각 행은 하루 한 번의 운동 효과가 아니라, 평소 일평균 활동시간이 다른 집단을 비교한 관찰 모형값입니다.",
          "en": "Each row is an observational model contrast between habitual mean daily activity doses, not the effect of one exercise minute performed today."
        },
        {
          "ko": "상대 HR 차이이며 개인의 절대위험 변화나 인과효과가 아닙니다.",
          "en": "This is a relative hazard contrast, not an individual absolute-risk change or causal effect."
        },
        {
          "ko": "연령·성별·인종은 보정변수이며, 이 곡선은 해당 집단별 효과곡선이 아닙니다.",
          "en": "Age, sex, and ethnicity were adjustment variables; these are not subgroup-specific curves."
        }
      ]
    },
    {
      "id": "cardiovascularMortality.vigorous.biswas-2025",
      "renderingGroup": "cardiovascularMortality.biswas-2025",
      "evidenceForm": "authorPublishedSourceCurve",
      "minuteSeriesStatus": "availableFromAuthorPublishedSourceCurve",
      "recommendedForRendering": true,
      "outcome": {
        "id": "cardiovascularMortality",
        "domain": "cardiovascular",
        "label": {
          "ko": "심혈관 사망",
          "en": "Cardiovascular mortality"
        },
        "endpoint": {
          "ko": "심혈관질환에 의한 사망",
          "en": "Death attributed to cardiovascular disease"
        }
      },
      "intensity": {
        "id": "vigorous",
        "abbreviation": "VPA",
        "label": {
          "ko": "고강도 신체활동(VPA)",
          "en": "Vigorous-intensity physical activity (VPA)"
        }
      },
      "source": {
        "id": "biswas.nature-communications.2025.corrected",
        "citation": "Biswas RK, et al. Wearable device-based health equivalence of different physical activity intensities against mortality, cardiometabolic disease, and cancer. Nature Communications. 2025;16:8315.",
        "journal": "Nature Communications",
        "publicationYear": 2025,
        "doi": "10.1038/s41467-025-63475-2",
        "url": "https://www.nature.com/articles/s41467-025-63475-2",
        "sourceDataUrl": "https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41467-025-63475-2/MediaObjects/41467_2025_63475_MOESM10_ESM.xlsx",
        "journalQuartile": "Q1",
        "quartileReviewedAt": "2026-08-11T00:00:00Z",
        "overlapGroup": "uk-biobank-accelerometry"
      },
      "population": {
        "participantCount": 67499,
        "eventCount": 545,
        "meanAgeYears": 61.6,
        "ageSDYears": 7.9,
        "femalePercent": 56.4,
        "whitePercent": 96.2
      },
      "exposure": {
        "reportedUnit": "minutePerDay",
        "timeBasis": "habitualMeanMinutePerDayFromWearableAssessment",
        "referenceMinutePerDay": 0,
        "authorSourceCurveGridStepMinute": 0.01,
        "sourceCurveMaximumMinutePerDay": 27.28,
        "includedIntegerMinuteMaximum": 27,
        "sourceSampling": "Exact author-published source-curve rows where Primary_exposure is an integer; no averaging and no interpolation"
      },
      "model": {
        "type": "FineGraySubdistributionHazardSpline",
        "mutuallyAdjustedForOtherIntensityEnergyExpenditure": true,
        "referentMinutePerDay": 0,
        "sourceDataUrl": "https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41467-025-63475-2/MediaObjects/41467_2025_63475_MOESM10_ESM.xlsx"
      },
      "points": [
        {
          "minutePerDay": 0,
          "hazardRatio": 1,
          "lowerConfidenceBound": 1,
          "upperConfidenceBound": 1,
          "relativeHazardDifferenceFromReferencePercent": 0,
          "nextMinuteHazardRatio": 0.858532,
          "nextMinuteHazardRatioChange": -0.141468,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 14.147
        },
        {
          "minutePerDay": 1,
          "hazardRatio": 0.858532,
          "lowerConfidenceBound": 0.813992,
          "upperConfidenceBound": 0.905509,
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          "nextMinuteHazardRatio": 0.738552,
          "nextMinuteHazardRatioChange": -0.11998,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 11.998
        },
        {
          "minutePerDay": 2,
          "hazardRatio": 0.738552,
          "lowerConfidenceBound": 0.664556,
          "upperConfidenceBound": 0.820787,
          "relativeHazardDifferenceFromReferencePercent": 26.145,
          "nextMinuteHazardRatio": 0.640408,
          "nextMinuteHazardRatioChange": -0.098144,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 9.814
        },
        {
          "minutePerDay": 3,
          "hazardRatio": 0.640408,
          "lowerConfidenceBound": 0.549003,
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          "nextMinuteHazardRatio": 0.563344,
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          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 7.706
        },
        {
          "minutePerDay": 4,
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        {
          "minutePerDay": 5,
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          "upperConfidenceBound": 0.634451,
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          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 4.347
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        {
          "minutePerDay": 6,
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          "upperConfidenceBound": 0.593594,
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        {
          "minutePerDay": 7,
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          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 2.424
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        {
          "minutePerDay": 8,
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        {
          "minutePerDay": 9,
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        {
          "minutePerDay": 10,
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        {
          "minutePerDay": 11,
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        {
          "minutePerDay": 12,
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        {
          "minutePerDay": 14,
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          "upperConfidenceBound": 0.462121,
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        {
          "minutePerDay": 15,
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        {
          "minutePerDay": 16,
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        {
          "minutePerDay": 17,
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          "lowerConfidenceBound": 0.255668,
          "upperConfidenceBound": 0.458397,
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        {
          "minutePerDay": 18,
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        {
          "minutePerDay": 20,
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        {
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          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.263
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        {
          "minutePerDay": 22,
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          "lowerConfidenceBound": 0.228305,
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          "nextMinuteHazardRatio": 0.326343,
          "nextMinuteHazardRatioChange": -0.002613,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.261
        },
        {
          "minutePerDay": 23,
          "hazardRatio": 0.326343,
          "lowerConfidenceBound": 0.222124,
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          "nextMinuteHazardRatio": 0.32375,
          "nextMinuteHazardRatioChange": -0.002593,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.259
        },
        {
          "minutePerDay": 24,
          "hazardRatio": 0.32375,
          "lowerConfidenceBound": 0.21587,
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          "nextMinuteHazardRatioChange": -0.002572,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.257
        },
        {
          "minutePerDay": 25,
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          "lowerConfidenceBound": 0.209593,
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          "nextMinuteHazardRatioChange": -0.002552,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.255
        },
        {
          "minutePerDay": 26,
          "hazardRatio": 0.318627,
          "lowerConfidenceBound": 0.203334,
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          "nextMinuteHazardRatio": 0.316095,
          "nextMinuteHazardRatioChange": -0.002531,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.253
        },
        {
          "minutePerDay": 27,
          "hazardRatio": 0.316095,
          "lowerConfidenceBound": 0.197124,
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          "nextMinuteHazardRatio": null,
          "nextMinuteHazardRatioChange": null,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": null
        }
      ],
      "limitations": [
        {
          "ko": "각 행은 하루 한 번의 운동 효과가 아니라, 평소 일평균 활동시간이 다른 집단을 비교한 관찰 모형값입니다.",
          "en": "Each row is an observational model contrast between habitual mean daily activity doses, not the effect of one exercise minute performed today."
        },
        {
          "ko": "상대 HR 차이이며 개인의 절대위험 변화나 인과효과가 아닙니다.",
          "en": "This is a relative hazard contrast, not an individual absolute-risk change or causal effect."
        },
        {
          "ko": "연령·성별·인종은 보정변수이며, 이 곡선은 해당 집단별 효과곡선이 아닙니다.",
          "en": "Age, sex, and ethnicity were adjustment variables; these are not subgroup-specific curves."
        }
      ]
    },
    {
      "id": "type2Diabetes.moderate.biswas-2025",
      "renderingGroup": "type2Diabetes.biswas-2025",
      "evidenceForm": "authorPublishedSourceCurve",
      "minuteSeriesStatus": "availableFromAuthorPublishedSourceCurve",
      "recommendedForRendering": true,
      "outcome": {
        "id": "type2Diabetes",
        "domain": "type2Diabetes",
        "label": {
          "ko": "제2형 당뇨병 발생",
          "en": "Incident type 2 diabetes"
        },
        "endpoint": {
          "ko": "신규 제2형 당뇨병",
          "en": "New type 2 diabetes"
        }
      },
      "intensity": {
        "id": "moderate",
        "abbreviation": "MPA",
        "label": {
          "ko": "중강도 신체활동(MPA)",
          "en": "Moderate-intensity physical activity (MPA)"
        }
      },
      "source": {
        "id": "biswas.nature-communications.2025.corrected",
        "citation": "Biswas RK, et al. Wearable device-based health equivalence of different physical activity intensities against mortality, cardiometabolic disease, and cancer. Nature Communications. 2025;16:8315.",
        "journal": "Nature Communications",
        "publicationYear": 2025,
        "doi": "10.1038/s41467-025-63475-2",
        "url": "https://www.nature.com/articles/s41467-025-63475-2",
        "sourceDataUrl": "https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41467-025-63475-2/MediaObjects/41467_2025_63475_MOESM10_ESM.xlsx",
        "journalQuartile": "Q1",
        "quartileReviewedAt": "2026-08-11T00:00:00Z",
        "overlapGroup": "uk-biobank-accelerometry"
      },
      "population": {
        "participantCount": 71533,
        "eventCount": 1836,
        "meanAgeYears": 61.6,
        "ageSDYears": 7.9,
        "femalePercent": 56.4,
        "whitePercent": 96.2
      },
      "exposure": {
        "reportedUnit": "minutePerDay",
        "timeBasis": "habitualMeanMinutePerDayFromWearableAssessment",
        "referenceMinutePerDay": 0,
        "authorSourceCurveGridStepMinute": 0.01,
        "sourceCurveMaximumMinutePerDay": 90.78,
        "includedIntegerMinuteMaximum": 90,
        "sourceSampling": "Exact author-published source-curve rows where Primary_exposure is an integer; no averaging and no interpolation"
      },
      "model": {
        "type": "FineGraySubdistributionHazardSpline",
        "mutuallyAdjustedForOtherIntensityEnergyExpenditure": true,
        "referentMinutePerDay": 0,
        "sourceDataUrl": "https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41467-025-63475-2/MediaObjects/41467_2025_63475_MOESM10_ESM.xlsx"
      },
      "points": [
        {
          "minutePerDay": 0,
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          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 1.17
        },
        {
          "minutePerDay": 1,
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          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 1.156
        },
        {
          "minutePerDay": 2,
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        },
        {
          "minutePerDay": 3,
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        {
          "minutePerDay": 4,
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        {
          "minutePerDay": 5,
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        {
          "minutePerDay": 6,
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        {
          "minutePerDay": 7,
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        {
          "minutePerDay": 8,
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        {
          "minutePerDay": 9,
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          "nextMinuteHazardRatioChange": -0.010523,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 1.052
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        {
          "minutePerDay": 10,
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          "nextMinuteHazardRatioChange": -0.010397,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 1.04
        },
        {
          "minutePerDay": 11,
          "hazardRatio": 0.878585,
          "lowerConfidenceBound": 0.817872,
          "upperConfidenceBound": 0.943805,
          "relativeHazardDifferenceFromReferencePercent": 12.141,
          "nextMinuteHazardRatio": 0.868327,
          "nextMinuteHazardRatioChange": -0.010258,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 1.026
        },
        {
          "minutePerDay": 12,
          "hazardRatio": 0.868327,
          "lowerConfidenceBound": 0.803099,
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        {
          "minutePerDay": 74,
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          "nextMinuteHazardRatio": 0.588638,
          "nextMinuteHazardRatioChange": -0.002048,
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        },
        {
          "minutePerDay": 75,
          "hazardRatio": 0.588638,
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          "upperConfidenceBound": 0.715871,
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        },
        {
          "minutePerDay": 76,
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          "upperConfidenceBound": 0.714894,
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          "nextMinuteHazardRatioChange": -0.002034,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.203
        },
        {
          "minutePerDay": 77,
          "hazardRatio": 0.584564,
          "lowerConfidenceBound": 0.478603,
          "upperConfidenceBound": 0.713984,
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          "nextMinuteHazardRatio": 0.582537,
          "nextMinuteHazardRatioChange": -0.002027,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.203
        },
        {
          "minutePerDay": 78,
          "hazardRatio": 0.582537,
          "lowerConfidenceBound": 0.475855,
          "upperConfidenceBound": 0.713137,
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          "nextMinuteHazardRatio": 0.580517,
          "nextMinuteHazardRatioChange": -0.00202,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.202
        },
        {
          "minutePerDay": 79,
          "hazardRatio": 0.580517,
          "lowerConfidenceBound": 0.473082,
          "upperConfidenceBound": 0.712351,
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          "nextMinuteHazardRatio": 0.578505,
          "nextMinuteHazardRatioChange": -0.002013,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.201
        },
        {
          "minutePerDay": 80,
          "hazardRatio": 0.578505,
          "lowerConfidenceBound": 0.470287,
          "upperConfidenceBound": 0.711624,
          "relativeHazardDifferenceFromReferencePercent": 42.15,
          "nextMinuteHazardRatio": 0.576499,
          "nextMinuteHazardRatioChange": -0.002006,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.201
        },
        {
          "minutePerDay": 81,
          "hazardRatio": 0.576499,
          "lowerConfidenceBound": 0.467472,
          "upperConfidenceBound": 0.710954,
          "relativeHazardDifferenceFromReferencePercent": 42.35,
          "nextMinuteHazardRatio": 0.5745,
          "nextMinuteHazardRatioChange": -0.001999,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.2
        },
        {
          "minutePerDay": 82,
          "hazardRatio": 0.5745,
          "lowerConfidenceBound": 0.464638,
          "upperConfidenceBound": 0.710339,
          "relativeHazardDifferenceFromReferencePercent": 42.55,
          "nextMinuteHazardRatio": 0.572508,
          "nextMinuteHazardRatioChange": -0.001992,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.199
        },
        {
          "minutePerDay": 83,
          "hazardRatio": 0.572508,
          "lowerConfidenceBound": 0.461788,
          "upperConfidenceBound": 0.709776,
          "relativeHazardDifferenceFromReferencePercent": 42.749,
          "nextMinuteHazardRatio": 0.570524,
          "nextMinuteHazardRatioChange": -0.001985,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.198
        },
        {
          "minutePerDay": 84,
          "hazardRatio": 0.570524,
          "lowerConfidenceBound": 0.458923,
          "upperConfidenceBound": 0.709264,
          "relativeHazardDifferenceFromReferencePercent": 42.948,
          "nextMinuteHazardRatio": 0.568545,
          "nextMinuteHazardRatioChange": -0.001978,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.198
        },
        {
          "minutePerDay": 85,
          "hazardRatio": 0.568545,
          "lowerConfidenceBound": 0.456044,
          "upperConfidenceBound": 0.7088,
          "relativeHazardDifferenceFromReferencePercent": 43.145,
          "nextMinuteHazardRatio": 0.566574,
          "nextMinuteHazardRatioChange": -0.001971,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.197
        },
        {
          "minutePerDay": 86,
          "hazardRatio": 0.566574,
          "lowerConfidenceBound": 0.453154,
          "upperConfidenceBound": 0.708383,
          "relativeHazardDifferenceFromReferencePercent": 43.343,
          "nextMinuteHazardRatio": 0.56461,
          "nextMinuteHazardRatioChange": -0.001964,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.196
        },
        {
          "minutePerDay": 87,
          "hazardRatio": 0.56461,
          "lowerConfidenceBound": 0.450254,
          "upperConfidenceBound": 0.70801,
          "relativeHazardDifferenceFromReferencePercent": 43.539,
          "nextMinuteHazardRatio": 0.562652,
          "nextMinuteHazardRatioChange": -0.001958,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.196
        },
        {
          "minutePerDay": 88,
          "hazardRatio": 0.562652,
          "lowerConfidenceBound": 0.447346,
          "upperConfidenceBound": 0.707681,
          "relativeHazardDifferenceFromReferencePercent": 43.735,
          "nextMinuteHazardRatio": 0.560702,
          "nextMinuteHazardRatioChange": -0.001951,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.195
        },
        {
          "minutePerDay": 89,
          "hazardRatio": 0.560702,
          "lowerConfidenceBound": 0.44443,
          "upperConfidenceBound": 0.707392,
          "relativeHazardDifferenceFromReferencePercent": 43.93,
          "nextMinuteHazardRatio": 0.558758,
          "nextMinuteHazardRatioChange": -0.001944,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.194
        },
        {
          "minutePerDay": 90,
          "hazardRatio": 0.558758,
          "lowerConfidenceBound": 0.441509,
          "upperConfidenceBound": 0.707144,
          "relativeHazardDifferenceFromReferencePercent": 44.124,
          "nextMinuteHazardRatio": null,
          "nextMinuteHazardRatioChange": null,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": null
        }
      ],
      "limitations": [
        {
          "ko": "각 행은 하루 한 번의 운동 효과가 아니라, 평소 일평균 활동시간이 다른 집단을 비교한 관찰 모형값입니다.",
          "en": "Each row is an observational model contrast between habitual mean daily activity doses, not the effect of one exercise minute performed today."
        },
        {
          "ko": "상대 HR 차이이며 개인의 절대위험 변화나 인과효과가 아닙니다.",
          "en": "This is a relative hazard contrast, not an individual absolute-risk change or causal effect."
        },
        {
          "ko": "연령·성별·인종은 보정변수이며, 이 곡선은 해당 집단별 효과곡선이 아닙니다.",
          "en": "Age, sex, and ethnicity were adjustment variables; these are not subgroup-specific curves."
        }
      ]
    },
    {
      "id": "type2Diabetes.vigorous.biswas-2025",
      "renderingGroup": "type2Diabetes.biswas-2025",
      "evidenceForm": "authorPublishedSourceCurve",
      "minuteSeriesStatus": "availableFromAuthorPublishedSourceCurve",
      "recommendedForRendering": true,
      "outcome": {
        "id": "type2Diabetes",
        "domain": "type2Diabetes",
        "label": {
          "ko": "제2형 당뇨병 발생",
          "en": "Incident type 2 diabetes"
        },
        "endpoint": {
          "ko": "신규 제2형 당뇨병",
          "en": "New type 2 diabetes"
        }
      },
      "intensity": {
        "id": "vigorous",
        "abbreviation": "VPA",
        "label": {
          "ko": "고강도 신체활동(VPA)",
          "en": "Vigorous-intensity physical activity (VPA)"
        }
      },
      "source": {
        "id": "biswas.nature-communications.2025.corrected",
        "citation": "Biswas RK, et al. Wearable device-based health equivalence of different physical activity intensities against mortality, cardiometabolic disease, and cancer. Nature Communications. 2025;16:8315.",
        "journal": "Nature Communications",
        "publicationYear": 2025,
        "doi": "10.1038/s41467-025-63475-2",
        "url": "https://www.nature.com/articles/s41467-025-63475-2",
        "sourceDataUrl": "https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41467-025-63475-2/MediaObjects/41467_2025_63475_MOESM10_ESM.xlsx",
        "journalQuartile": "Q1",
        "quartileReviewedAt": "2026-08-11T00:00:00Z",
        "overlapGroup": "uk-biobank-accelerometry"
      },
      "population": {
        "participantCount": 71533,
        "eventCount": 1836,
        "meanAgeYears": 61.6,
        "ageSDYears": 7.9,
        "femalePercent": 56.4,
        "whitePercent": 96.2
      },
      "exposure": {
        "reportedUnit": "minutePerDay",
        "timeBasis": "habitualMeanMinutePerDayFromWearableAssessment",
        "referenceMinutePerDay": 0,
        "authorSourceCurveGridStepMinute": 0.01,
        "sourceCurveMaximumMinutePerDay": 27.28,
        "includedIntegerMinuteMaximum": 27,
        "sourceSampling": "Exact author-published source-curve rows where Primary_exposure is an integer; no averaging and no interpolation"
      },
      "model": {
        "type": "FineGraySubdistributionHazardSpline",
        "mutuallyAdjustedForOtherIntensityEnergyExpenditure": true,
        "referentMinutePerDay": 0,
        "sourceDataUrl": "https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41467-025-63475-2/MediaObjects/41467_2025_63475_MOESM10_ESM.xlsx"
      },
      "points": [
        {
          "minutePerDay": 0,
          "hazardRatio": 1,
          "lowerConfidenceBound": 1,
          "upperConfidenceBound": 1,
          "relativeHazardDifferenceFromReferencePercent": 0,
          "nextMinuteHazardRatio": 0.897001,
          "nextMinuteHazardRatioChange": -0.102999,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 10.3
        },
        {
          "minutePerDay": 1,
          "hazardRatio": 0.897001,
          "lowerConfidenceBound": 0.871216,
          "upperConfidenceBound": 0.923549,
          "relativeHazardDifferenceFromReferencePercent": 10.3,
          "nextMinuteHazardRatio": 0.805836,
          "nextMinuteHazardRatioChange": -0.091165,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 9.117
        },
        {
          "minutePerDay": 2,
          "hazardRatio": 0.805836,
          "lowerConfidenceBound": 0.760592,
          "upperConfidenceBound": 0.853771,
          "relativeHazardDifferenceFromReferencePercent": 19.416,
          "nextMinuteHazardRatio": 0.728329,
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          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 7.751
        },
        {
          "minutePerDay": 3,
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          "lowerConfidenceBound": 0.669504,
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          "relativeHazardDifferenceFromReferencePercent": 27.167,
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          "nextMinuteHazardRatioChange": -0.062812,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 6.281
        },
        {
          "minutePerDay": 4,
          "hazardRatio": 0.665517,
          "lowerConfidenceBound": 0.598151,
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          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 4.856
        },
        {
          "minutePerDay": 5,
          "hazardRatio": 0.616957,
          "lowerConfidenceBound": 0.54495,
          "upperConfidenceBound": 0.698478,
          "relativeHazardDifferenceFromReferencePercent": 38.304,
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          "nextMinuteHazardRatioChange": -0.037103,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 3.71
        },
        {
          "minutePerDay": 6,
          "hazardRatio": 0.579854,
          "lowerConfidenceBound": 0.505757,
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          "relativeHazardDifferenceFromReferencePercent": 42.015,
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        },
        {
          "minutePerDay": 7,
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        },
        {
          "minutePerDay": 8,
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        },
        {
          "minutePerDay": 9,
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          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 1.101
        },
        {
          "minutePerDay": 10,
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        },
        {
          "minutePerDay": 11,
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        },
        {
          "minutePerDay": 12,
          "hazardRatio": 0.491672,
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        {
          "minutePerDay": 13,
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          "lowerConfidenceBound": 0.420742,
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          "nextMinuteHazardRatio": 0.486317,
          "nextMinuteHazardRatioChange": -0.002154,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.215
        },
        {
          "minutePerDay": 14,
          "hazardRatio": 0.486317,
          "lowerConfidenceBound": 0.419062,
          "upperConfidenceBound": 0.564365,
          "relativeHazardDifferenceFromReferencePercent": 51.368,
          "nextMinuteHazardRatio": 0.48451,
          "nextMinuteHazardRatioChange": -0.001806,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.181
        },
        {
          "minutePerDay": 15,
          "hazardRatio": 0.48451,
          "lowerConfidenceBound": 0.417143,
          "upperConfidenceBound": 0.562758,
          "relativeHazardDifferenceFromReferencePercent": 51.549,
          "nextMinuteHazardRatio": 0.482722,
          "nextMinuteHazardRatioChange": -0.001789,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.179
        },
        {
          "minutePerDay": 16,
          "hazardRatio": 0.482722,
          "lowerConfidenceBound": 0.414647,
          "upperConfidenceBound": 0.561972,
          "relativeHazardDifferenceFromReferencePercent": 51.728,
          "nextMinuteHazardRatio": 0.480939,
          "nextMinuteHazardRatioChange": -0.001782,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.178
        },
        {
          "minutePerDay": 17,
          "hazardRatio": 0.480939,
          "lowerConfidenceBound": 0.4116,
          "upperConfidenceBound": 0.56196,
          "relativeHazardDifferenceFromReferencePercent": 51.906,
          "nextMinuteHazardRatio": 0.479164,
          "nextMinuteHazardRatioChange": -0.001776,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.178
        },
        {
          "minutePerDay": 18,
          "hazardRatio": 0.479164,
          "lowerConfidenceBound": 0.408054,
          "upperConfidenceBound": 0.562667,
          "relativeHazardDifferenceFromReferencePercent": 52.084,
          "nextMinuteHazardRatio": 0.477395,
          "nextMinuteHazardRatioChange": -0.001769,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.177
        },
        {
          "minutePerDay": 19,
          "hazardRatio": 0.477395,
          "lowerConfidenceBound": 0.404066,
          "upperConfidenceBound": 0.564031,
          "relativeHazardDifferenceFromReferencePercent": 52.261,
          "nextMinuteHazardRatio": 0.475633,
          "nextMinuteHazardRatioChange": -0.001762,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.176
        },
        {
          "minutePerDay": 20,
          "hazardRatio": 0.475633,
          "lowerConfidenceBound": 0.399701,
          "upperConfidenceBound": 0.565989,
          "relativeHazardDifferenceFromReferencePercent": 52.437,
          "nextMinuteHazardRatio": 0.473877,
          "nextMinuteHazardRatioChange": -0.001756,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.176
        },
        {
          "minutePerDay": 21,
          "hazardRatio": 0.473877,
          "lowerConfidenceBound": 0.395019,
          "upperConfidenceBound": 0.568476,
          "relativeHazardDifferenceFromReferencePercent": 52.612,
          "nextMinuteHazardRatio": 0.472127,
          "nextMinuteHazardRatioChange": -0.001749,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.175
        },
        {
          "minutePerDay": 22,
          "hazardRatio": 0.472127,
          "lowerConfidenceBound": 0.390079,
          "upperConfidenceBound": 0.571433,
          "relativeHazardDifferenceFromReferencePercent": 52.787,
          "nextMinuteHazardRatio": 0.470384,
          "nextMinuteHazardRatioChange": -0.001743,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.174
        },
        {
          "minutePerDay": 23,
          "hazardRatio": 0.470384,
          "lowerConfidenceBound": 0.384933,
          "upperConfidenceBound": 0.574805,
          "relativeHazardDifferenceFromReferencePercent": 52.962,
          "nextMinuteHazardRatio": 0.468648,
          "nextMinuteHazardRatioChange": -0.001737,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.174
        },
        {
          "minutePerDay": 24,
          "hazardRatio": 0.468648,
          "lowerConfidenceBound": 0.379626,
          "upperConfidenceBound": 0.578544,
          "relativeHazardDifferenceFromReferencePercent": 53.135,
          "nextMinuteHazardRatio": 0.466917,
          "nextMinuteHazardRatioChange": -0.00173,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.173
        },
        {
          "minutePerDay": 25,
          "hazardRatio": 0.466917,
          "lowerConfidenceBound": 0.374199,
          "upperConfidenceBound": 0.58261,
          "relativeHazardDifferenceFromReferencePercent": 53.308,
          "nextMinuteHazardRatio": 0.465194,
          "nextMinuteHazardRatioChange": -0.001724,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.172
        },
        {
          "minutePerDay": 26,
          "hazardRatio": 0.465194,
          "lowerConfidenceBound": 0.368684,
          "upperConfidenceBound": 0.586966,
          "relativeHazardDifferenceFromReferencePercent": 53.481,
          "nextMinuteHazardRatio": 0.463476,
          "nextMinuteHazardRatioChange": -0.001717,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": 0.172
        },
        {
          "minutePerDay": 27,
          "hazardRatio": 0.463476,
          "lowerConfidenceBound": 0.363111,
          "upperConfidenceBound": 0.591583,
          "relativeHazardDifferenceFromReferencePercent": 53.652,
          "nextMinuteHazardRatio": null,
          "nextMinuteHazardRatioChange": null,
          "nextMinuteRelativeHazardDifferenceIncreasePercentagePoints": null
        }
      ],
      "limitations": [
        {
          "ko": "각 행은 하루 한 번의 운동 효과가 아니라, 평소 일평균 활동시간이 다른 집단을 비교한 관찰 모형값입니다.",
          "en": "Each row is an observational model contrast between habitual mean daily activity doses, not the effect of one exercise minute performed today."
        },
        {
          "ko": "상대 HR 차이이며 개인의 절대위험 변화나 인과효과가 아닙니다.",
          "en": "This is a relative hazard contrast, not an individual absolute-risk change or causal effect."
        },
        {
          "ko": "연령·성별·인종은 보정변수이며, 이 곡선은 해당 집단별 효과곡선이 아닙니다.",
          "en": "Age, sex, and ethnicity were adjustment variables; these are not subgroup-specific curves."
        }
      ]
    },
    {
      "id": "heartFailure.moderate.ho-2022",
      "renderingGroup": "heartFailure.ho-2022",
      "evidenceForm": "reportedCategories",
      "minuteSeriesStatus": "notEstimableFromReportedData",
      "recommendedForRendering": true,
      "outcome": {
        "id": "heartFailure",
        "domain": "cardiovascular",
        "label": {
          "ko": "심부전 발생",
          "en": "Incident heart failure"
        },
        "endpoint": {
          "ko": "의료기록 기반 신규 심부전",
          "en": "New heart failure identified from linked medical records"
        }
      },
      "intensity": {
        "id": "moderate",
        "abbreviation": "MPA",
        "label": {
          "ko": "중강도 신체활동(MPA)",
          "en": "Moderate-intensity physical activity (MPA)"
        }
      },
      "source": {
        "id": "ho.circulation.2022",
        "citation": "Ho FK, et al. Device-measured physical activity and incident heart failure. Circulation. 2022.",
        "journal": "Circulation",
        "publicationYear": 2022,
        "doi": "10.1161/CIRCULATIONAHA.122.059663",
        "url": "https://doi.org/10.1161/CIRCULATIONAHA.122.059663",
        "journalQuartile": "Q1",
        "quartileReviewedAt": "2026-08-11T00:00:00Z",
        "overlapGroup": "uk-biobank-accelerometry"
      },
      "population": {
        "participantCount": 94739,
        "meanAgeYears": 56.1,
        "femalePercent": 56.9,
        "whitePercent": 96.6
      },
      "exposure": {
        "reportedUnit": "minutePerWeek",
        "timeBasis": "reportedWeeklyCategory",
        "sourceCategoriesAreAuthoritative": true
      },
      "analysis": {
        "mutuallyAdjustedForOtherIntensity": true
      },
      "reportedCategories": [
        {
          "ordinal": 0,
          "reportedRangeLabel": "0–<150분/주",
          "isReference": true,
          "hazardRatio": 1
        },
        {
          "ordinal": 1,
          "reportedRangeLabel": "150–<300분/주",
          "isReference": false,
          "hazardRatio": 0.54,
          "lowerConfidenceBound": 0.46,
          "upperConfidenceBound": 0.64
        },
        {
          "ordinal": 2,
          "reportedRangeLabel": "300–<600분/주",
          "isReference": false,
          "hazardRatio": 0.36,
          "lowerConfidenceBound": 0.3,
          "upperConfidenceBound": 0.43
        },
        {
          "ordinal": 3,
          "reportedRangeLabel": "≥600분/주",
          "isReference": false,
          "hazardRatio": 0.28,
          "lowerConfidenceBound": 0.22,
          "upperConfidenceBound": 0.35
        }
      ],
      "minuteSeriesUnavailableReason": {
        "ko": "논문은 주당 시간 범주의 HR만 보고했으므로 범주 안의 특정 분에 HR을 배정할 수 없습니다.",
        "en": "The paper reported HRs for weekly-time categories, so an HR cannot be assigned to a specific minute within a category."
      },
      "limitations": [
        {
          "ko": "자유생활 전체 활동이며 구조화 운동시간과 동일하지 않습니다.",
          "en": "This is total free-living activity, not structured exercise time."
        }
      ]
    },
    {
      "id": "heartFailure.vigorous.ho-2022",
      "renderingGroup": "heartFailure.ho-2022",
      "evidenceForm": "reportedCategories",
      "minuteSeriesStatus": "notEstimableFromReportedData",
      "recommendedForRendering": true,
      "outcome": {
        "id": "heartFailure",
        "domain": "cardiovascular",
        "label": {
          "ko": "심부전 발생",
          "en": "Incident heart failure"
        },
        "endpoint": {
          "ko": "의료기록 기반 신규 심부전",
          "en": "New heart failure identified from linked medical records"
        }
      },
      "intensity": {
        "id": "vigorous",
        "abbreviation": "VPA",
        "label": {
          "ko": "고강도 신체활동(VPA)",
          "en": "Vigorous-intensity physical activity (VPA)"
        }
      },
      "source": {
        "id": "ho.circulation.2022",
        "citation": "Ho FK, et al. Device-measured physical activity and incident heart failure. Circulation. 2022.",
        "journal": "Circulation",
        "publicationYear": 2022,
        "doi": "10.1161/CIRCULATIONAHA.122.059663",
        "url": "https://doi.org/10.1161/CIRCULATIONAHA.122.059663",
        "journalQuartile": "Q1",
        "quartileReviewedAt": "2026-08-11T00:00:00Z",
        "overlapGroup": "uk-biobank-accelerometry"
      },
      "population": {
        "participantCount": 94739,
        "meanAgeYears": 56.1,
        "femalePercent": 56.9,
        "whitePercent": 96.6
      },
      "exposure": {
        "reportedUnit": "minutePerWeek",
        "timeBasis": "reportedWeeklyCategory",
        "sourceCategoriesAreAuthoritative": true
      },
      "analysis": {
        "mutuallyAdjustedForOtherIntensity": true
      },
      "reportedCategories": [
        {
          "ordinal": 0,
          "reportedRangeLabel": "0–<25분/주",
          "isReference": true,
          "hazardRatio": 1
        },
        {
          "ordinal": 1,
          "reportedRangeLabel": "25–<50분/주",
          "isReference": false,
          "hazardRatio": 0.83,
          "lowerConfidenceBound": 0.69,
          "upperConfidenceBound": 0.99
        },
        {
          "ordinal": 2,
          "reportedRangeLabel": "50–<75분/주",
          "isReference": false,
          "hazardRatio": 0.78,
          "lowerConfidenceBound": 0.61,
          "upperConfidenceBound": 1.01
        },
        {
          "ordinal": 3,
          "reportedRangeLabel": "≥75분/주",
          "isReference": false,
          "hazardRatio": 0.7,
          "lowerConfidenceBound": 0.51,
          "upperConfidenceBound": 0.95
        }
      ],
      "minuteSeriesUnavailableReason": {
        "ko": "논문은 주당 시간 범주의 HR만 보고했으므로 범주 안의 특정 분에 HR을 배정할 수 없습니다.",
        "en": "The paper reported HRs for weekly-time categories, so an HR cannot be assigned to a specific minute within a category."
      },
      "limitations": [
        {
          "ko": "자유생활 전체 활동이며 구조화 운동시간과 동일하지 않습니다.",
          "en": "This is total free-living activity, not structured exercise time."
        }
      ]
    },
    {
      "id": "type2Diabetes.moderate.boonpor-2023",
      "renderingGroup": "type2Diabetes.boonpor-2023.categories",
      "evidenceForm": "reportedCategories",
      "minuteSeriesStatus": "notEstimableFromReportedData",
      "recommendedForRendering": false,
      "outcome": {
        "id": "type2Diabetes",
        "domain": "type2Diabetes",
        "label": {
          "ko": "제2형 당뇨병 발생",
          "en": "Incident type 2 diabetes"
        },
        "endpoint": {
          "ko": "신규 제2형 당뇨병",
          "en": "New type 2 diabetes"
        }
      },
      "intensity": {
        "id": "moderate",
        "abbreviation": "MPA",
        "label": {
          "ko": "중강도 신체활동(MPA)",
          "en": "Moderate-intensity physical activity (MPA)"
        }
      },
      "source": {
        "id": "boonpor.bmc-medicine.2023",
        "citation": "Boonpor J, et al. BMC Medicine. 2023;21:191.",
        "journal": "BMC Medicine",
        "publicationYear": 2023,
        "doi": "10.1186/s12916-023-02851-5",
        "url": "https://doi.org/10.1186/s12916-023-02851-5",
        "journalQuartile": "Q1",
        "quartileReviewedAt": "2026-08-11T00:00:00Z",
        "overlapGroup": "uk-biobank-accelerometry"
      },
      "population": {
        "participantCount": 40431,
        "eventCount": 591,
        "femalePercent": 57.6,
        "whitePercent": 97.4
      },
      "exposure": {
        "reportedUnit": "minutePerWeek",
        "timeBasis": "reportedWeeklyCategory",
        "sourceCategoriesAreAuthoritative": true
      },
      "analysis": {
        "mutuallyAdjustedForOtherIntensity": true
      },
      "reportedCategories": [
        {
          "ordinal": 0,
          "reportedRangeLabel": "<150분/주",
          "isReference": true,
          "hazardRatio": 1
        },
        {
          "ordinal": 1,
          "reportedRangeLabel": "150–<300분/주",
          "isReference": false,
          "hazardRatio": 0.51,
          "lowerConfidenceBound": 0.38,
          "upperConfidenceBound": 0.68
        },
        {
          "ordinal": 2,
          "reportedRangeLabel": "300–<600분/주",
          "isReference": false,
          "hazardRatio": 0.38,
          "lowerConfidenceBound": 0.29,
          "upperConfidenceBound": 0.5
        },
        {
          "ordinal": 3,
          "reportedRangeLabel": "≥600분/주",
          "isReference": false,
          "hazardRatio": 0.29,
          "lowerConfidenceBound": 0.2,
          "upperConfidenceBound": 0.41
        }
      ],
      "minuteSeriesUnavailableReason": {
        "ko": "논문은 주당 시간 범주의 HR만 보고했으므로 범주 안의 특정 분에 HR을 배정할 수 없습니다.",
        "en": "The paper reported HRs for weekly-time categories, so an HR cannot be assigned to a specific minute within a category."
      },
      "limitations": [
        {
          "ko": "범주형 보완근거로만 보존하며 분별 계산에는 사용하지 않습니다.",
          "en": "Retained as categorical supporting evidence only; it is not used for minute-level calculations."
        }
      ]
    },
    {
      "id": "type2Diabetes.vigorous.boonpor-2023",
      "renderingGroup": "type2Diabetes.boonpor-2023.categories",
      "evidenceForm": "reportedCategories",
      "minuteSeriesStatus": "notEstimableFromReportedData",
      "recommendedForRendering": false,
      "outcome": {
        "id": "type2Diabetes",
        "domain": "type2Diabetes",
        "label": {
          "ko": "제2형 당뇨병 발생",
          "en": "Incident type 2 diabetes"
        },
        "endpoint": {
          "ko": "신규 제2형 당뇨병",
          "en": "New type 2 diabetes"
        }
      },
      "intensity": {
        "id": "vigorous",
        "abbreviation": "VPA",
        "label": {
          "ko": "고강도 신체활동(VPA)",
          "en": "Vigorous-intensity physical activity (VPA)"
        }
      },
      "source": {
        "id": "boonpor.bmc-medicine.2023",
        "citation": "Boonpor J, et al. BMC Medicine. 2023;21:191.",
        "journal": "BMC Medicine",
        "publicationYear": 2023,
        "doi": "10.1186/s12916-023-02851-5",
        "url": "https://doi.org/10.1186/s12916-023-02851-5",
        "journalQuartile": "Q1",
        "quartileReviewedAt": "2026-08-11T00:00:00Z",
        "overlapGroup": "uk-biobank-accelerometry"
      },
      "population": {
        "participantCount": 40431,
        "eventCount": 591,
        "femalePercent": 57.6,
        "whitePercent": 97.4
      },
      "exposure": {
        "reportedUnit": "minutePerWeek",
        "timeBasis": "reportedWeeklyCategory",
        "sourceCategoriesAreAuthoritative": true
      },
      "analysis": {
        "mutuallyAdjustedForOtherIntensity": true
      },
      "reportedCategories": [
        {
          "ordinal": 0,
          "reportedRangeLabel": "<25분/주",
          "isReference": true,
          "hazardRatio": 1
        },
        {
          "ordinal": 1,
          "reportedRangeLabel": "25–<50분/주",
          "isReference": false,
          "hazardRatio": 0.62,
          "lowerConfidenceBound": 0.52,
          "upperConfidenceBound": 0.77
        },
        {
          "ordinal": 2,
          "reportedRangeLabel": "50–<75분/주",
          "isReference": false,
          "hazardRatio": 0.52,
          "lowerConfidenceBound": 0.36,
          "upperConfidenceBound": 0.77
        },
        {
          "ordinal": 3,
          "reportedRangeLabel": "≥75분/주",
          "isReference": false,
          "hazardRatio": 0.36,
          "lowerConfidenceBound": 0.22,
          "upperConfidenceBound": 0.58
        }
      ],
      "minuteSeriesUnavailableReason": {
        "ko": "논문은 주당 시간 범주의 HR만 보고했으므로 범주 안의 특정 분에 HR을 배정할 수 없습니다.",
        "en": "The paper reported HRs for weekly-time categories, so an HR cannot be assigned to a specific minute within a category."
      },
      "limitations": [
        {
          "ko": "범주형 보완근거로만 보존하며 분별 계산에는 사용하지 않습니다.",
          "en": "Retained as categorical supporting evidence only; it is not used for minute-level calculations."
        }
      ]
    },
    {
      "id": "cerebrovascularDisease.moderate.ramakrishnan-2021-corrected",
      "renderingGroup": "cerebrovascularDisease.ramakrishnan-2021-corrected",
      "evidenceForm": "reportedCategories",
      "minuteSeriesStatus": "notEstimableFromReportedData",
      "recommendedForRendering": true,
      "outcome": {
        "id": "cerebrovascularDisease",
        "domain": "cerebrovascular",
        "label": {
          "ko": "뇌혈관질환 발생",
          "en": "Incident cerebrovascular disease"
        },
        "endpoint": {
          "ko": "ICD-10 I60–I69 복합결과; 뇌졸중 단독이 아님",
          "en": "ICD-10 I60–I69 composite; not stroke alone"
        }
      },
      "intensity": {
        "id": "moderate",
        "abbreviation": "MPA",
        "label": {
          "ko": "중강도 신체활동(MPA)",
          "en": "Moderate-intensity physical activity (MPA)"
        }
      },
      "source": {
        "id": "ramakrishnan.plos-medicine.2021.corrected",
        "citation": "Ramakrishnan R, et al. PLOS Medicine. 2021;18:e1003487. Corrected by e1003809.",
        "journal": "PLOS Medicine",
        "publicationYear": 2021,
        "doi": "10.1371/journal.pmed.1003487",
        "correctionDoi": "10.1371/journal.pmed.1003809",
        "url": "https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1003809",
        "journalQuartile": "Q1",
        "quartileReviewedAt": "2026-08-11T00:00:00Z",
        "overlapGroup": "uk-biobank-accelerometry"
      },
      "population": {
        "participantCount": 90211,
        "eventCount": 933,
        "meanAgeYears": 62,
        "ageSDYears": 7.8,
        "femalePercent": 57.9,
        "whitePercent": 97
      },
      "exposure": {
        "reportedUnit": "minutePerWeek",
        "timeBasis": "reportedWeeklyCategory",
        "sourceCategoriesAreAuthoritative": true
      },
      "analysis": {
        "mutuallyAdjustedForOtherIntensity": false
      },
      "reportedCategories": [
        {
          "ordinal": 0,
          "reportedRangeLabel": "<524.17분/주",
          "isReference": true,
          "hazardRatio": 1
        },
        {
          "ordinal": 1,
          "reportedRangeLabel": "524.17–705.60분/주",
          "isReference": false,
          "hazardRatio": 0.77,
          "lowerConfidenceBound": 0.66,
          "upperConfidenceBound": 0.91
        },
        {
          "ordinal": 2,
          "reportedRangeLabel": "705.61–927.36분/주",
          "isReference": false,
          "hazardRatio": 0.62,
          "lowerConfidenceBound": 0.51,
          "upperConfidenceBound": 0.74
        },
        {
          "ordinal": 3,
          "reportedRangeLabel": "≥927.37분/주",
          "isReference": false,
          "hazardRatio": 0.57,
          "lowerConfidenceBound": 0.46,
          "upperConfidenceBound": 0.69
        }
      ],
      "minuteSeriesUnavailableReason": {
        "ko": "논문은 주당 시간 범주의 HR만 보고했으므로 범주 안의 특정 분에 HR을 배정할 수 없습니다.",
        "en": "The paper reported HRs for weekly-time categories, so an HR cannot be assigned to a specific minute within a category."
      },
      "limitations": [
        {
          "ko": "뇌졸중 단독이 아닌 뇌혈관질환 복합결과입니다.",
          "en": "The endpoint is cerebrovascular disease, not stroke alone."
        },
        {
          "ko": "MPA와 VPA를 서로 보정하지 않아 두 HR을 결합할 수 없습니다.",
          "en": "MPA and VPA were not mutually adjusted, so their HRs cannot be combined."
        }
      ]
    },
    {
      "id": "cerebrovascularDisease.vigorous.ramakrishnan-2021-corrected",
      "renderingGroup": "cerebrovascularDisease.ramakrishnan-2021-corrected",
      "evidenceForm": "reportedCategories",
      "minuteSeriesStatus": "notEstimableFromReportedData",
      "recommendedForRendering": true,
      "outcome": {
        "id": "cerebrovascularDisease",
        "domain": "cerebrovascular",
        "label": {
          "ko": "뇌혈관질환 발생",
          "en": "Incident cerebrovascular disease"
        },
        "endpoint": {
          "ko": "ICD-10 I60–I69 복합결과; 뇌졸중 단독이 아님",
          "en": "ICD-10 I60–I69 composite; not stroke alone"
        }
      },
      "intensity": {
        "id": "vigorous",
        "abbreviation": "VPA",
        "label": {
          "ko": "고강도 신체활동(VPA)",
          "en": "Vigorous-intensity physical activity (VPA)"
        }
      },
      "source": {
        "id": "ramakrishnan.plos-medicine.2021.corrected",
        "citation": "Ramakrishnan R, et al. PLOS Medicine. 2021;18:e1003487. Corrected by e1003809.",
        "journal": "PLOS Medicine",
        "publicationYear": 2021,
        "doi": "10.1371/journal.pmed.1003487",
        "correctionDoi": "10.1371/journal.pmed.1003809",
        "url": "https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1003809",
        "journalQuartile": "Q1",
        "quartileReviewedAt": "2026-08-11T00:00:00Z",
        "overlapGroup": "uk-biobank-accelerometry"
      },
      "population": {
        "participantCount": 90211,
        "eventCount": 933,
        "meanAgeYears": 62,
        "ageSDYears": 7.8,
        "femalePercent": 57.9,
        "whitePercent": 97
      },
      "exposure": {
        "reportedUnit": "minutePerWeek",
        "timeBasis": "reportedWeeklyCategory",
        "sourceCategoriesAreAuthoritative": true
      },
      "analysis": {
        "mutuallyAdjustedForOtherIntensity": false
      },
      "reportedCategories": [
        {
          "ordinal": 0,
          "reportedRangeLabel": "<10.08분/주",
          "isReference": true,
          "hazardRatio": 1
        },
        {
          "ordinal": 1,
          "reportedRangeLabel": "10.09–20.15분/주",
          "isReference": false,
          "hazardRatio": 0.72,
          "lowerConfidenceBound": 0.61,
          "upperConfidenceBound": 0.86
        },
        {
          "ordinal": 2,
          "reportedRangeLabel": "20.16–40.31분/주",
          "isReference": false,
          "hazardRatio": 0.58,
          "lowerConfidenceBound": 0.48,
          "upperConfidenceBound": 0.7
        },
        {
          "ordinal": 3,
          "reportedRangeLabel": "≥40.32분/주",
          "isReference": false,
          "hazardRatio": 0.55,
          "lowerConfidenceBound": 0.45,
          "upperConfidenceBound": 0.67
        }
      ],
      "minuteSeriesUnavailableReason": {
        "ko": "논문은 주당 시간 범주의 HR만 보고했으므로 범주 안의 특정 분에 HR을 배정할 수 없습니다.",
        "en": "The paper reported HRs for weekly-time categories, so an HR cannot be assigned to a specific minute within a category."
      },
      "limitations": [
        {
          "ko": "뇌졸중 단독이 아닌 뇌혈관질환 복합결과입니다.",
          "en": "The endpoint is cerebrovascular disease, not stroke alone."
        },
        {
          "ko": "MPA와 VPA를 서로 보정하지 않아 두 HR을 결합할 수 없습니다.",
          "en": "MPA and VPA were not mutually adjusted, so their HRs cannot be combined."
        }
      ]
    }
  ]
}